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Crude alkaloid extract of Rhazya stricta inhibits cell growth and sensitizes human lung cancer cells to cisplatin through induction of apoptosis Genet. Mol. Biol.
Elkady,Ayman I..
There is an urgent need to improve the clinical management of non-small cell lung cancer (NSCLC), one of the most frequent causes of cancer-related deaths in men and women worldwide. Rhazya stricta, an important medicinal plant used in traditional Oriental medicine, possesses anti-oxidant, anti-carcinogenic and free radical scavenging properties. This study was done to explore the potential anticancer activity of a crude alkaloid extract of R. stricta (CAERS) against the NSCLC line A549. CAERS markedly suppressed the growth of A549 cells and considerably enhanced the anti-proliferative potential of cisplatin. CAERS-mediated inhibition of A549 cell growth correlated with the induction of apoptosis that was accompanied by numerous morphological changes, DNA...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Apoptosis; Lung cancer; Medicinal plant; RT-PCR; Western blot.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572013000100003
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Cytokinins in the in vitro multiplication and analysis of the volatile fraction of Hyptis marrubioides Rev. Ciênc. Agron.
Rodrigues,Mariane Aparecida; Bertolucci,Suzan Kelly Vilela; Alvarenga,Ivan Caldeira Almeida; Silva,Sâmia Torres; Carvalho,Alexandre Alves de; Pinto,José Eduardo Brasil Pereira.
ABSTRACT The aim of this study was to evaluate different concentrations of two cytokinins in the in vitro propagation of the medicinal plant Hyptis marrubioides Epl. and to analyse the volatile fraction of the compounds. Nodal segments of plants were inoculated onto Murashige and Skoog (MS) solid medium with different concentrations of benzylaminopurine (BAP) or tidiazuron (TDZ) under a 16/8 h light/dark cycle at 25 ± 2 °C. After 45 days growth, the plants were evaluated for the number and length of the shoots and for shoot dry matter. The volatile constituents were analysed by headspace-GC/MS. The greatest number of shoots was obtained with 1.0 mg L-1 TDZ in the MS medium. The greatest values ​​for shoot length and dry matter were obtained with BAP....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Growth regulators; Proliferation; Terpenes; Medicinal plant; Hyptis smarrubioides.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-66902019000100090
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Drying kinetics of blackberry leaves AGRIAMBI
Martins,Elton A. S.; Goneli,André L. D.; Goncalves,Alexandre A.; Hartmann Filho,Cesar P.; Siqueira,Valdiney C.; Oba,Guilherme C..
ABSTRACT Blackberry leaves have some pharmacological properties and one of the most widespread and studied uses is to relieve symptoms of the climacteric and other symptoms during the premenstrual period. Thus, drying becomes important for the conservation and storage of the product until its use or processing. The present study aimed to evaluate the drying kinetics of blackberry leaves, as well as to determine the effective diffusion coefficient and the activation energy during the drying process. Blackberry leaves were dried in an experimental fixed-bed dryer under four controlled temperature conditions (40, 50, 60 and 70 °C) and two drying air speeds (0.4 and 0.8 m s-1). With the experimental data of moisture ratio, eight mathematical models were fitted...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Morus nigra L.; Medicinal plant; Air speeds; Midilli model.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-43662018000800570
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Drying temperature changes trichome integrity, chemical content and composition of the essential oil of pepper-rosmarin Ciência Rural
Queiroz,Giovanna Alcântara; Silva,Pedro Henrique Lopes; Oliveira,Rosilene Aparecida de; Sodré,George Andrade; Costa,Larissa Corrêa do Bomfim.
ABSTRACT: Medicinal plants are generally commercialized dried. However, temperatures used in their drying processes may interfere with the content and chemical composition of their essential oils. The Lippia origanoides possesses thymol in the essential oil that is stored in glandular trichomes. Thymol is a major component of economic importance in the chemical and pharmaceutical industry. The objective of this study was to evaluate the effect of the drying temperatures of L. origanoides leaves regarding trichome integrity, content, and chemical composition of the essential oil. The experimental design was completely randomized with four treatments defined by oven drying temperatures (40, 50, 60, and 70ºC) and four replications. Essential oil was...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Lippia origanoides; Medicinal plant; Secretory structures; Drying; Thymol.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782018001100404
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Effects of temperature and pre-germinative treatments on seed germination of Talinum triangulare (Jacq. ) willd (Portulacaceae) Rev. bras. sementes
Brasileiro,Beatriz Gonçalves; Dias,Denise Cunha F. S.; Casali,Vicente Wagner Dias; Bhering,Maria Carmen; Cecon,Paulo Roberto.
The objective of this study was to evaluate the effects of temperature, substrate and pre-germinative treatments on T. triangulare seeds. Four temperatures (constant 20, 25, 30 °C and alternate 20-30 °C) and two types of seeding (on paper and between paper), with light, were evaluated. The pre-germinative treatments evaluated included: immersion in water (24 hours), immersion in 6% hypochlorite solution (1 hour), immersion in 0.2% potassium nitrate solution (24 hours), immersion in 0.05% gibberellin solution (24 hours) and the control (untreated seeds). The highest germination percentage was observed at the alternate temperatures of 20-30 ºC, but with no significant difference between the substrates at this temperature. Soaking seeds in KNO3 gave the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Substrate; Germination; Dormancy; Medicinal plant.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-31222010000400017
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Essential oil production of lemongrass (Cymbopogon citratus) under organic compost containing sewage sludge AGRIAMBI
d'Ávila,Júlia V.; Martinazzo,Ana P.; Santos,Fabiana S. dos; Teodoro,Carlos E. de S.; Portz,Adriano.
ABSTRACT One of the main urban polluting agents are the sewers, which even with proper treatment end up generating a polluting waste, the sewage sludge. One of the options for the disposal of this sludge is the use in agriculture, due to its high content of organic matter and nutrients. This study aimed to use urban sewage sludge for lemongrass cultivation and essential oil production. The plants were grown in soil containing different organic compost doses (0, 5, 10, 20, 40 and 60 t ha-1), formed from the sewage sludge composting process and waste of urban vegetation pruning. At harvest, plants were analyzed for the concentration of nutrients, chlorophyll content, number of tillers, biomass production, essential oil content and the microbiological quality...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Solid waste; Medicinal plant; Composting; Mineral nutrition.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-43662016000900811
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Ethnomedicinal plants used for snakebite treatments in Ethiopia: a comprehensive overview J. Venom. Anim. Toxins incl. Trop. Dis.
Yirgu,Abraham; Chippaux,Jean-Philippe.
Abstract Traditional medicine plays an important role in the daily lives of people living in rural parts of Ethiopia. Despite the fact that Ethiopia has a long history of using traditional medicinal plants as an alternative medicine source, there is no checklist compiling these plants used for snakebite treatment. This review collected and compiled available knowledge on and practical usage of such plants in the country. A literature review on medicinal plants used to treat snakebites was conducted from 67 journal articles, PhD dissertation and MSc theses available online. Data that summarize scientific and folk names, administration methods, plant portion used for treatment and method of preparation of recipes were organized and analyzed based on citation...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Ethnobotany; Medicinal plant; Traditional treatment; Snakebite; Envenomation; Sub-Saharan Africa; Ethiopia.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992019000100205
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Evaluation of antinociceptive and anti-inflammatory activities of the topical preparation of Cipura paludosa (Iridaceae) Acta Amazonica
Silva Neto,José Antônio Paixão da; Menezes,Larissa Dias; Gomes,Gúbio Oliveira; Cunha,Elise Marques Freire; Azevedo,Mariângela Soares de; Ferreira,Vania Moraes; Silva,Mônica Valero da.
Alho do mato (Cipura paludosa, Iridaceae) is a medicinal plant found in the Amazon rain forest, North of Brazil. It has been used to treat algic, inflammatory and infectious processes. The aim of this study was to evaluate the anti-inflammatory and antinociceptive action of the crude Cipura paludosa ethanolic extract at concentrations ranging between 2.0 and 4.0% in Oil and Water cream formulations for topical use. The physical-chemical stability of the formulations was monitored over a six-month period with the use of accelerated stability tests. In order to evaluate the anti-inflammatory and antinociceptive activities, we used a paw edema test induced by carrageenan and a formalin test, respectively. The paw edema test showed that there was a statistical...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Oil and Water Cream; Medicinal plant; Paw edema test; Formalin test.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672014000200012
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Evaluation of wound healing and antimicrobial properties of aqueous extract from Bowdichia virgilioides stem barks in mice Anais da ABC (AABC)
AGRA,ISABELA K.R.; PIRES,LUANA L.S.; CARVALHO,PAULO S.M.; SILVA-FILHO,EURÍPEDES A.; SMANIOTTO,SALETE; BARRETO,EMILIANO.
The decoction of the stem barks from Bowdichia virgilioides KUNTH is a folk remedy used to treat inflammatory disorders in Latin American and Brazil. In the present study, the wound healing activity of aqueous extract of the stem bark from B. virgilioides, called AEBv, was evaluated by the rate of healing by wound contraction and period of epithelization at different days post-wound using the wound excisional model. On day 9, the AEBv-treated animals exhibited significative reduction in the wound area when compared with controls. In wound infected with S. aureus, the AEBv significantly improved the wound contraction when compared to the saline-treated mice. The histological analysis showed that AEBv induced a collagen deposition, increase in the fibroblast...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Wound healing; Antimicrobial effect; Bowdichia virgilioides; Medicinal plant.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652013000300945
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Extract of Solidago chilensis Meyen inflorescences: cytotoxicity and inhibitory activity on nitric oxide synthesis in activated macrophage cell line J774A.1 BJPS
Brito,Thais Morais de; Amendoeira,Fabio Coelho; Oliveira,Temistocles Barroso de; Frutuoso,Valber da Silva; Ferraris,Fausto Klabund; Valverde,Simone Sacramento.
Solidago chilensis Meyen (= Solidago microglossa) popularly known as “Brazilian arnica” is used to treat of inflammatory disorders. S. chilensis is constant in the Therapeutic Memento of the Rio de Janeiro city and belongs to the medicinal species of Brazilian National List of Medicinal Plants of Interest of the Unified National Health System (SUS). There are no studies in the literature showing the direct activity of this plant species on immune system cells. The present study evaluated the chemical composition as well as the cytotoxic and pharmacological activity of the ether-ethanol extract from S. chilensis inflorescences (SCIE) in murine macrophage cell line J774A.1. The results showed that higher concentrations (50 to 200 µg/mL) of SCIE had...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Anti-inflammatory activity; Medicinal plant; Asteraceae; Diterpenes; Flavonoids.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100594
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Genetic diversity among natural populations of Mandevilla velutina Horticultura Brasileira
Bertoni,Bianca Waléria; Souza,Ana Valéria de; Biondo,Ronaldo; França,Suzelei de C; Telles,Mariana PC; Pereira,Ana Maria S.
Mandevilla velutina (Mart. Ex Stadelm) Woodson (Apocynaceae) is an endemic species in the Cerrado (Brazilian Savannah), whose alcoholic extracts and root infusions are extensively used in the popular medicine to treat inflammatory diseases and against snake bites. Currently, this species has been pointed out as crucial in conservation programs. Therefore, studies on its genetic diversity, as well as the development of methodology for in vitro conservation in germplasm banks are imperative to avoid its extinction. The objective of this work was to investigate the intra- and inter-populational genetic variability of M. velutina to enhance the representativeness of germplasm banks. To this aim, we used RAPD molecular markers. The analysis of molecular...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Mandevilla velutina; Medicinal plant; Extinction risk; Molecular markers.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-05362010000200012
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Genetic diversity of Lippia rotundifolia Cham. in Minas Gerais, Brazil Biological Sciences
Meira, Messulan Rodrigues; Martins, Ernane Ronie; Resende, Luciane Vilela.
Lippia rotundifolia is an aromatic species, endemic from Campos rupestres and isolated by mountains. We aimed with the research to study the genetic variability of chá-de-pedestre (Lippia rotundifolia Cham.) with natural occurrence in ten places of the State of Minas Gerais, from molecular markers of ISSR type. The places of collection were: Parque Estadual de Serra Nova; Parque Estadual Veredas do Peruaçu; Abóboras community; Gigante community; edge of Rio do Peixe; environmental preservation area of Olhos d´água; private property in Joaquim Felício; Parque Estadual do Rio Preto; São Gonçalo do Rio das Pedras and brook of Rio Tigre. After the establishment of the extraction and amplification of DNA fragments with primers ISSR, an array of genetic distance...
Tipo: Info:eu-repo/semantics/article Palavras-chave: 2.02.03.00-4 pedestrian tea; Genetic variability; Medicinal plant; Conservation Genética Vegetal.
Ano: 2019 URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/42754
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Genotoxic potential of the latex from cotton-leaf physicnut (Jatropha gossypiifolia L.) Genet. Mol. Biol.
de Almeida,Pedro Marcos; de Sousa Araújo,Silvany; Marin-Morales,Maria Aparecida; Benko-Iseppon,Ana Maria; Brasileiro-Vidal,Ana Christina.
Jatropha gossypiifolia L. (Euphorbiaceae), popularly known as cotton-leaf physicnut, is a milky shrub notable for its medicinal properties. The present study aimed to evaluate the toxic, cytotoxic and genotoxic effects of the latex of J. gossypiifolia, using Allium cepa L. as test system. Seeds of A. cepa were exposed to five concentrations of the latex (1.25; 2.5; 5; 10 and 20 mL/L) in order to evaluate parameters of toxicity (evaluation of root growth), cytotoxicity (mitotic index frequency) and genotoxicity (frequency of chromosome alterations). The latex showed a significant decrease in root mean growth value as well as mitotic index for the tested concentrations, except for 1.25 mL/L, when compared to results from the negative control. The 1.25, 2.5...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Allium cepa test; Medicinal plant; Plant latex; Genotoxicity evaluation.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572015000100093
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Growth analysis of Fafia in relation to the propagation method used Horticultura Brasileira
May,André; Bovi,Odair A; Maia,Nilson B; Moraes,Andrea RA de; Pinheiro,Mariane Q.
A trial was carried out in Campinas, Brazil, from August 2005 to August 2006, in order to analyze the effect of two propagation methods (seeds and cuttings) on the development of Pfaffia glomerata (Spreng.) Pedersen. The experimental design was a completely randomized block, with five replications, and two methods of plant propagation. Plant height, aerial part dry mass and root dry mass were evaluated. Plants propagated from cuttings showed greater accumulation of dry mass on the aerial part. Root dry mass accumulation curves showed an exponential pattern, and at the end of the experimental period, the average of roots dry mass for both treatments were similar, up to 349,65 g plant-1.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Pfaffia glomerata; Brazilian ginseng; Medicinal plant; Propagation.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-05362008000300016
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Growth and volatiles in the micropropagation of Santa Maria herb Rev. Ciênc. Agron.
Carvalho,Alexandre Alves de; Bertolucci,Suzan Kelly Vilela; Silva,Sâmia Torres; Pinto,José Eduardo Brasil Pereira.
ABSTRACT The aims of this study were to establish micropropagation for Chenopodium ambrosioides L. and analysis of volatile constituents in vitro as a function of different salt concentrations of MS medium and sucrose. The apical buds were established on MS medium added with 3% sucrose. The vegetative growth of nodal segments was tested in different salt concentrations of MS basic medium (0.25, 0.50, 1.00, 1.50, and 2.00) and of sucrose (5, 10, 20, 30, and 40 g L-1). Nodal and apical segments were tested in vertical and horizontal orientations. Different volumes of culture medium (20; 35, 50, 65, and 80 mL) were examined in the growth of nodal segments. Plants were acclimatized in three different substrates. The apical segments collected from matrices...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Chenopodium ambrosioides L.; Medicinal plant; Tissue culture.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-66902018000400624
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Harvest time and plant age on the content and chemical composition of the essential oil of Alpinia zerumbet Horticultura Brasileira
Santos,Martiely S; Jezler,Caroline N; Oliveira,Ariana RMF de; Oliveira,Rosilene A; Mielke,Marcelo S; Costa,Larissa CB.
Alpinia zerumbet is an aromatic and medicinal plant rich in essential oil, known as colônia. Essential oils are derived from secondary metabolism and may be a source of raw materials for cosmetic, pharmaceutical, food and perfumery industry. The plant secondary metabolism and biosynthetic activity can vary according to endogenous and exogenous factors to which it is exposed. In this context, in this study we evaluated the influence of harvest time and plant age of Alpinia zerumbet on biomass and essential oil production. For the harvest time experiment the plants of A. zerumbet were harvested at different times (8, 10, 12, 14, 16 and 18 h), using a completely randomized design with four replications. In the plant age experiment the seedlings were...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Zingiberaceae; 'colônia'; Medicinal plant; GC analysis; Terpinen-4-ol.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-05362012000300005
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Histochemistry, content and chemical composition of essential oil in different organs of Alpinia zerumbet Ciência Rural
Jezler,Caroline Nery; Batista,Ricardo Silva; Alves,Péricles Barreto; Silva,Delmira da Costa; Costa,Larissa Corrêa do Bomfim.
Alpinia zerumbet is a medicinal plant from Asian origin used in folk medicine for the treatment of hypertension, which effect is attributed to terpinen-4-ol, the major component of the essential oil. The objective of this work was to identify the essential oil secretory structures in the leaf, flower, root and rhizome of this plant, and analyze the content and the chemical composition of the oil in the different organs of the plant. Sections were subjected to histochemical test with Nadi reagent for in situ localization of secretion. The essential oil extraction was performed by hydrodistillation in a Clevenger apparatus and the compounds were identified in CG-EM/FID. The histochemical test was positive for terpenoids, confirming the presence of essential...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Medicinal plant; Terpinen-4-ol; Secretory structure.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782013001000013
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Importance of anatomical leaf-blade features for the characterization of medicinal Commelinaceae in the Rio de la Plata area (Argentina) Boletín de la Sociedad
Novoa,María C; Arambarri,Ana M.
In this paper we examine the leaf-blade anatomy of: Commelina erecta L. var. erecta f. erecta, Tradescantia fluminensis Vell., Tripogandra diuretica (Mart.) Handlos, and T. glandulosa (Seub.) Rohweder. These species grow in the coastal region of the Río de la Plata (Argentina) where they are used as ophthalmic, diuretic, antirheumatic, sudorific, and digestive. The aim of this study was to establish diagnostic features in order to deepen knowledge of these medicinal species and thus, get a valuable tool to establish their botanical identity. The leaves were prepared according to usual methods for light and scanning electron microscopes. Histochemical techniques to identify starch, lipophilic substances, mucilage, tannins, and oxalate salts were performed....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Anatomy; Commelina; Leaf-blade; Medicinal plant; Tradescantia; Tripogandra.
Ano: 2016 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1851-23722016000300002
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Improvement of friable callus production of Boerhaavia paniculata Rich and the investigation of its lipid profile by GC/MS Anais da ABC (AABC)
SOUZA,JOANNE M.M.; BERKOV,STRAHILL; SANTOS,ALBERDAN S..
In this study, a protocol to induce high amount of friable callus of Boerhaavia paniculata RICH and a lipidomics technique were applied to investigate the profile of lipids to relate to those present in the roots of this plant that presented anti-inflammatory activity in the crude hexane extract. The callus culture was induced from seeds in solidified Murashige and Skoog medium containing different amounts of glucose and different concentrations of 2,4-Dichlorophenoxyacetic acid. The explants were kept in a germination chamber at 30±2°C with a photoperiod of 16 h under light intensity of 27 µmol m–2 s–1 for 4 weeks. The best results for friable callus formation and development of the biomass were obtained in the treatment containing 2.26 µM 2.4-D and...
Palavras-chave: Anti-inflammatory lipids; Boerhaavia paniculata; Callus culture; Lipid profile; Medicinal plant.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652014000301015
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In vitro establishment of pepper-rosmarin nodal segments Horticultura Brasileira
Blank,Arie F; Costa,Andréa S da; Arrigoni-Blank,Maria de Fátima; Mendonça,Aline B de; Ledo,Ana da S.
Pepper-rosmarin (Lippia sidoides Cham.) is a native medicinal plant from the Brazilian biome Caatinga. Its high economical importance comes from the antimicrobial properties of thymol and carvacrol, both present in the pepper-rosmarin essential oil. Nodal segments of pepper-rosmarin were established in vitro to evaluate different growth regulators. We tested four concentrations of IBA (0.0; 0.01; 0.05; and 0.1 mg L-1) combined with six concentrations of BAP (0.0; 0.1; 0.5; 1.0; 2.0; and 4.0 mg L-1) in assay 1; five concentrations of NAA (0.0; 0.1; 0.25; 0.5; and 1.0 mg L-1) in assay 2; two concentrations of NAA (0.0 and 0.01 mg L-1) combined with five concentrations of kinetin (0.0; 0.25; 0.5; 1.0; and 2.0 mg L-1) in assay 3; five concentrations of IAA...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Lippia sidoides; Medicinal plant; Micropropagation; Growth regulator.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-05362008000200025
Registros recuperados: 85
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